5G robotic telesurgery: Revolutionary medical approach (literature review)
https://doi.org/10.63769/3033-6392-2026-1-2-8-22
Abstract
Background. The problem of uneven distribution of quality medical resources and limited access to highly qualified surgical help for patients from distant regions has existed for a long time. 5G-based telesurgery opens up the prospects for overcoming geographical barriers. However, its clinical use is still at the starting stage.
Aim. To analyze perioperative outcomes and safety profile of robot-assisted surgeries performed remotely using 5G-based systems.
Materials and methods. Systematic search of sources in the PubMed, Embase, Web of Science and Cochrane Library databases was performed. The analysis included clinical trials added to the databases since their creation and until April 10, 2026. Special attention was paid to the articles on radical gastrectomy due to stomach cancer, as well as hepatopancreatobiliary and urological surgery. The key limitations of these interventions were identified. Descriptions of single-patient clinical cases were excluded from the analysis.
Results. Oncological gastroenterology: 2 Chinese studies, prospective single-center (n = 27) and retrospective (n = 10), demonstrated that 100 % of resections were R0. Perioperative outcomes were similar to outcomes of non-remote robot-assisted surgery, delay of the roundtrip signal was only 31–91 ms. Hepatopancreatobiliary surgery: 3 studies (n = 5, n = 6, n = 20) confirmed the possibility of remote cholecystectomy and liver resection with delay of 43–126 ms; episodic network disruptions were observed but they did not affect safety of the surgery. Urology: 5 studies (between 6 and 37 patients) involving radical prostatectomy, nephrectomy, adrenalectomy, and other interventions with success rates up to 100 % and identical perioperative outcomes as in non-remote surgeries (delay varied between 29.1 and 129.6 ms). All studies share the same limitations of small sample sizes, absence of data on long-term oncological outcomes, variability of network characteristics, absence of tactile feedback in robotized systems, absence of ethical and legal base, and uncertain economic efficiency.
Conclusion. Feasibility and safety of robot-assisted surgeries performed remotely using 5G networks was demonstrated in cases of carefully selected patients. Perioperative outcomes of remote and non-remote robot-assisted surgeries are similar. However, telesurgery is still at the early stage of validation and carries many uncertainties and limitations; currently, it cannot replace non-remote robot-assisted surgery.
About the Authors
Y. QiangRussian Federation
Yinpeng Qiang
8–2 Trubetskaya St., Moscow 119991
F. P. Vetshev
Russian Federation
8–2 Trubetskaya St., Moscow 119991
S. V. Osminin
Russian Federation
8–2 Trubetskaya St., Moscow 119991
I. R. Bilyalov
Russian Federation
8–2 Trubetskaya St., Moscow 119991
E. V. Panina
Russian Federation
8–2 Trubetskaya St., Moscow 119991
N. V. Petukhova
Russian Federation
8–2 Trubetskaya St., Moscow 119991
References
1. Kim W., Kim H.-H., Han S.-U. et al. Decreased morbidity of laparoscopic distal gastrectomy compared with open distal gastrectomy for stage I gastric cancer: short-term outcomes from a multicenter randomized controlled trial (KLASS-01). Ann Surg 2016;263(1):28–35. DOI: 10.1097/SLA.0000000000001346
2. Lee H.-J., Hyung W.J., Yang H.-K. et al. Short-term outcomes of a multicenter randomized controlled trial comparing laparoscopic distal gastrectomy with D2 lymphadenectomy to open distal gastrectomy for locally advanced gastric cancer (KLASS-02-RCT). Ann Surg 2019;270(6):983–91. DOI: 10.1097/SLA.0000000000003217
3. Katai H., Mizusawa J., Katayama H. et al. Short-term surgical outcomes from a phase III study of laparoscopy-assisted versus open distal gastrectomy with nodal dissection for clinical stage IA/IB gastric cancer: Japan Clinical Oncology Group Study JCOG0912. Gastric Cancer 2017;20(4):699–708. DOI: 10.1007/s10120-016-0646-9
4. Hu Y., Huang C., Sun Y. et al. Morbidity and mortality of laparoscopic versus open D2 distal gastrectomy for advanced gastric cancer: a randomized controlled trial. J Clin Oncol 2016;34(12):1350–7. DOI: 10.1200/JCO.2015.63.7215
5. Kitano S., Iso Y., Moriyama M., Sugimachi K. Laparoscopy-assisted Billroth I gastrectomy. Surg Laparosc Endosc 1994;4(2):146–8.
6. Hashizume M., Sugimachi K. Robot-assisted gastric surgery. Surg Clin North Am 2003;83(6):1429–44. DOI: 10.1016/S0039-6109(03)00158-0
7. Ojima T., Nakamura M., Hayata K. et al. Short-term outcomes of robotic gastrectomy vs laparoscopic gastrectomy for patients with gastric cancer: a randomized clinical trial. JAMA Surg 2021;156(10):954–63. DOI: 10.1001/jamasurg.2021.3182
8. Lu J., Zheng C.-H., Xu B.-B. et al. Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer: a randomized controlled trial. Ann Surg 2021;273(5):858–67. DOI: 10.1097/SLA.0000000000004466
9. Lu J., Xu B.-B., Zheng H.-L. et al. Robotic versus laparoscopic distal gastrectomy for resectable gastric cancer: a randomized phase 2 trial. Nat Commun 2024;15(1):4668. DOI: 10.1038/s41467-024-49013-6
10. Pan H.-F., Wang G., Liu J. et al. Robotic versus laparoscopic gastrectomy for locally advanced gastric cancer. Surg Laparosc Endosc Percutan Tech 2017;27(6):428–33. DOI: 10.1097/SLE.0000000000000469
11. Silvestre J., Seeger S., Reitman C.A. Geographic disparities in the supply and adequacy of the general surgeon workforce across the United States: Projections to 2037. Am J Surg 2026;253:116685. DOI: 10.1016/j.amjsurg.2025.116685
12. Miller-Hammond K., Anderson D. Barriers to surgical health care access in rural communities. Am Surg 2025;91(5):681–4. DOI: 10.1177/00031348251323712
13. Xia S.-B., Lu Q.-S. Development status of telesurgery robotic system. Chin J Traumatol 2021;24(3):144–7. DOI: 10.1016/j.cjtee.2021.03.001
14. Xie X., Tian Y., Huang J. et al. Surgery without distance: will 5G-based robot-assisted telesurgery redefine modern surgery? Transl Lung Cancer Res 2025;14(5):1821–9. DOI: 10.21037/tlcr-2025-16
15. Ding Y., Wang S., Lan R. et al. Telerobotic surgery: a comprehensive two-decade evolution and the integration of emerging technologies. Int J Surg 2026;112(1):1652–72. DOI: 10.1097/JS9.0000000000003484
16. Marescaux J., Leroy J., Gagner M. et al. Transatlantic robot-assisted telesurgery. Nature 2001;413(6854):379–80. DOI: 10.1038/35096636
17. Georgiou K.E., Georgiou E., Satava R.M. 5G Use in healthcare: the future is present. JSLS 2021;25(4):e2021.00064. DOI: 10.4293/JSLS.2021.00064
18. Moustris G., Tzafestas C., Konstantinidis K. A long distance telesurgical demonstration on robotic surgery phantoms over 5G. Int J Comput Assist Radiol Surg 2023;18(9):1577–87. DOI: 10.1007/s11548-023-02913-2
19. Zhang M., Hu M., Yang J. et al. A pilot study on the clinical feasibility of 5G remote robot-assisted gastrectomy. World J Surg Oncol 2025;23(1):117. DOI: 10.1186/s12957-025-03780-8
20. Guo H., Tian Y., Ding P. et al. Safety and feasibility of robotassisted remote radical gastrectomy for gastric cancer based on 5G communication technology (FUTURE-04): a prospective, singlearm clinical trial. Gastric Cancer 2026;29(1):238–49. DOI: 10.1007/s10120-025-01687-7
21. Guo C., Zhou J., Hu M. et al. Clinical application and observation of 5G remote robotic radical gastrectomy for gastric cancer. Surg Endosc 2026;40(3):2127–35. DOI: 10.1007/s00464-025-12268-1
22. Kim T., Zimmerman P.M., Wade M.J., Weiss C.A. 3rd. The effect of delayed visual feedback on telerobotic surgery. Surg Endosc 2005;19(5):683–6. DOI: 10.1007/s00464-004-8926-6
23. Xu S., Perez M., Yang K. et al. Determination of the latency effects on surgical performance and the acceptable latency levels in telesurgery using the dV-Trainer simulator. Surg Endosc 2014;28(9):2569–76. DOI: 10.1007/s00464-014-3504-z
24. Ebihara Y., Hirano S., Kurashima Y. et al. Tele-robotic distal gastrectomy with lymph node dissection on a cadaver. Asian J Endosc Surg 2024;17(1):e13246. DOI: 10.1111/ases.13246
25. Fan Y., Ma C., Wu X. et al. 5G Remote robot-assisted hepatobiliary and pancreatic surgery: a report of five cases and a literature review. Int J Med Robot 2025;21(1):e70027. DOI: 10.1002/rcs.70027
26. Liao W., Zhu H.-T., Guo Y.-T. et al. Feasibility and safety of remote robotic hepatectomy: a prospective single-arm study with MP1000 system in China. EClinicalMedicine 2025;89:103579. DOI: 10.1016/j.eclinm.2025.103579
27. Yang J., Zhan W., Zhang Z. et al. The safety and feasibility of telerobotic cholecystectomy via a 5G network: a prospective controlled clinical trial. Surg Endosc 2025;39(11):7336–46. DOI: 10.1007/s00464-025-12005-8
28. Cuevas C.A.G., Alvarado G.A.D., González C.J. et al. Scientific evolution of robotic surgery in urogenital diseases: bibliometric analysis. J Robot Surg 2025;19(1):219. DOI: 10.1007/s11701-025-02359-5
29. Pan H.-M., Wu Y.-M., Lee W.-J. et al. The trends and evolution of robotic surgery in Taiwan: a 14-year nationwide analysis (2011–2024). J Robot Surg 2025;20(1):18. DOI: 10.1007/s11701-025-02987-x
30. Yu S., Tao J., Guo B. et al. Application of 5G robotic telesurgery in urology: a multicenter study in the real world. Surg Endosc 2025;39(9):5613–22. DOI: 10.1007/s00464-025-11969-x
31. Ye S., Peng D., Zhu L. et al. 5G-remote radical prostatectomy under novel robotic systems: a prospective comparative cohort study with local surgeries. Prostate Cancer Prostatic Dis 2025 Jul 28. DOI: 10.1038/s41391-025-01004-4. Epub ahead of print.
32. Li J., Jiao W., Yuan H. et al. Telerobot-assisted laparoscopic adrenalectomy: feasibility study. Br J Surg 2022;110(1):6–9. DOI: 10.1093/bjs/znac279
33. Li J., Yang X., Chu G. et al. Application of improved robot-assisted laparoscopic telesurgery with 5G technology in urology. Eur Urol 2023;83(1):41–4. DOI: 10.1016/j.eururo.2022.06.018
34. Wang Y., Ai Q., Zhao W. et al. Safety and reliability of a robotassisted laparoscopic telesurgery system: expanding indications in urological surgery. Eur Urol 2024;85(5):506–7. DOI: 10.1016/j.eururo.2023.11.002
35. Elendu C., Amaechi D.C., Elendu T.C. et al. The legal and ethical considerations in cross-border telesurgical procedures. Ann Med Surg (Lond) 2025;87(6):3660–72. DOI: 10.1097/MS9.0000000000003344
36. Motiwala Z.Y., Desai A., Bisht R. et al. Telesurgery: current status and strategies for latency reduction. J Robot Surg 2025;19(1):153. DOI: 10.1007/s11701-025-02333-1
37. Takano H., Ebihara Y., Hirano S. et al. Effectiveness of haptic feedback during local and remote robotic surgery: single-blind cadaveric study. J Robot Surg 2025;19(1):662. DOI: 10.1007/s11701-025-02826-z
38. Xue J., Weng S. Navigating the legal complexities of telesurgery in China: an assessment of tort liability and the path forward. Med Sci Law 2025;65(1):15–22. DOI: 10.1177/00258024241229831
39. Patel V., Saikali S., Moschovas M.C. et al. Technical and ethical considerations in telesurgery. J Robot Surg 2024;18(1):40. DOI: 10.1007/s11701-023-01797-3
Review
For citations:
Qiang Y., Vetshev F.P., Osminin S.V., Bilyalov I.R., Panina E.V., Petukhova N.V. 5G robotic telesurgery: Revolutionary medical approach (literature review). Medical Robotics. 2026;1(2):8-22. (In Russ.) https://doi.org/10.63769/3033-6392-2026-1-2-8-22
JATS XML
